This course will teach the core principles of evolutionary biology and the special challenges of applying them to problems in psychology and public health. The course will begin with the subset of core principles of evolutionary biology that have particular applications in psychology and public health. Some of the early classes will be divided into subsections so we can match teaching to the backgrounds of students from different areas. It will then survey the fast growing field of evolutionary medicine, what it offers to psychology and public health already, and new applications that are likely to be especially useful. Most of the detailed examples will be from infectious disease and evolutionary aspects of behavioral disorders and behaviors that influence disease susceptibility. The course will close by addressing the challenges of formulating and testing evolutionary hypotheses about why natural selection left our bodies vulnerable to diseases, emphasizing how new research questions emerge from an evolutionary perspective, and new methodologies for rigorously testing evolutionary hypotheses about disease. At the conclusion of the course, participants will understand how core principles of evolutionary biology have been and can be applied to public health problems, and they will have a moderately developed critical capacity for assessing research reports in the area.