Graduate Course Catalog
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Note: For descriptions of classes each term, see the LSA Course Guide
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Courses in MED Microbiology and Immunology
Microbiology (MICRBIOL)
MICRBIOL 405. Medical Microbiology & Infectious Diseases
BIOLOGY 207 and 305; and one of: MCDB 310, 311, BIOLCHEM 415 or 451, or CHEM 451. (Prerequisites enforced at registration.) (3). (BS). May not be repeated for credit. Rackham credit requires additional work.

MICRBIOL 415. Virology
BIOL207 and 305; and one of (MCDB/BIOL 310, MCDB/BIOL 311, BIOLCHEM 415, or BIOLCHEM/CHEM 451). (3). (BS). May not be repeated for credit. Rackham credit requires additional work.

MICRBIOL 440 / IMMUNO 440. Immunology
BIOLOGY 207 and 305; and one of: MCDB 310, 311, BIOLCHEM 415 or 451, or CHEM 451. (3). (BS). May not be repeated for credit. Only one of MICRBIOL 440 or IMMUNO 440 or MCDB 436 will count toward a Microbiology major. Rackham credit requires additional work.

MICRBIOL 460 / INTMED 460. Eukaryotic Microbiology
BIOLOGY 207 and 305; and one of: MCDB 310, 311, BIOCHEM 415 or 451 or CHEM 451. (3). (BS). May not be repeated for credit. F. Rackham credit requires additional work.

This upper level undergraduate course will cover the biology of eukaryotic microbes and the environments in which they live. Eukaryotic microbes include single-celled protozoa, multi-cellular helminths (worms), and fungi. This course will cover the complex life cycles (intermediate hosts, insect vectors) required for survival of many protozoa and helminths. Eukaryotic microbes are also a significant cause of human disease throughout the world (e.g. Malaria, Leishmaniasis, Trypanosomiasis, Giardiasis, Histoplasmosis, Blastomycosis). We will examine the evolutionary relationship between eukaryotic pathogens and their mammalian hosts, including the complex relationship between host immunity and pathogen immunoevasion. We will also discuss the renewed interest in Neglected Tropical Diseases (NTDs). NTDs are a group of diseases causing substantial illness in more than one billion people globally. The most common NTDs include Lymphatic Filariasis (Elephantiasis), Onchoceriasis (River Blindness), Sohistosomiasis, Soil-Transmitted Helminths, and Dracunculiasis (Guinea Work Disease).

MICRBIOL 504 / ANATOMY 504 / BIOLCHEM 504 / BIOMEDE 504. Cellular Biotechnology
(3). (BS). May not be repeated for credit.

MICRBIOL 607. Micro Pathogene I
Consent of instructor required. BIOCHM/GEN/PI. (3). (BS). May not be repeated for credit.

MICRBIOL 615. Molecular and Cellular Determinants of Viral Pathogenesis I
BIOLOGY,MICRBIOL 503 or permission of instructor. (2). (BS). May not be repeated for credit.

MICRBIOL 631 / BIOLCHEM 631 / BIOLOGY 631 / HUMGEN 631 / PHRMACOL 631. Genetic Program Student Seminar
Graduate standing and permission of instructor. (1). (BS). May not be repeated for credit.

MICRBIOL 632 / HUMGEN 632 / MCDB 632. Experimental Genetics Systems
Graduate standing, and current or past Genetics Training Program student. (1). (BS). May be elected three times for credit. F. This course has a grading basis of "S" or "U".

Two faculty members per session describe their application of genetics principles to analysis of specific biological questions. This new course is designed to provide Genetics Training Program students with systematic exposure to the range of genetics approaches in use within the Program, and to increase interaction between students and faculty in the program.

MICRBIOL 640. Molecular and Cellular Immunology
BIOLOGY 305, BIOLCHEM 415; Instructor permission for UG and NCFD. (3). (BS). May not be repeated for credit.

This course will be focused upon molecular and cellular aspects of the mammalian immune system. Topics include: Mechanisms of antigen recognition in innate and adaptive immunity; antigen processing and presentation; the MHC; generation of diversity in immune receptors; B and T cell development, activation, differentiation and effector function; phagocytes; NK cells and other innate immune cell types, immunological tolerance and its breakdown; microbial immunity; and signal transduction in the immune system. The course will include both didactic lectures and discussion-type seminars based upon contemporary research papers.

MICRBIOL 641. Advanced Immunology
MICRBIOL 640. (1). (BS). May not be repeated for credit.

Mechanisms that regulate immune cell development and function in health and disease will be covered in this advanced level immunology course, primarily through discussion of contemporary research papers. Together with MICRBIOL 640, this course is expected to lead to an in-depth understanding of the immune response at molecular and cellular levels.

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